Head over to https://github.com/second-state/ssvm-nodejs-starter to get started.

Use Docker:
$ docker pull secondstate/ssvm-nodejs-starter:v1
$ docker run -p 3000:3000 --rm -it -v $(pwd):/app secondstate/ssvm-nodejs-starter:v1
(docker) # cd /app
(docker) # ssvmup build
(docker) # node node/app.js

Copy the functions example - https://github.com/second-state/wasm-learning/tree/master/nodejs/functions

Replace the files and run your node app.

If you want to try out Machine learning with Rust - https://github.com/second-state/wasm-learning/tree/master/nodejs/ml